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谷春雨

谷春雨

主任醫(yī)師 講師

顱底病區(qū)副主任

掛 號 費:80元


出診時間:周四上午


專業(yè)特長:顱內(nèi)腫瘤、顱底腫瘤、聽神經(jīng)瘤、垂體瘤、腦膜瘤等


個人簡歷

神經(jīng)外科博士,留美博士后,主任醫(yī)師,1999于中國醫(yī)科大學(xué)獲臨床醫(yī)學(xué)學(xué)士學(xué)位;2003年于中國醫(yī)科大學(xué)獲神經(jīng)外科碩士學(xué)位; 同年于中國醫(yī)科大學(xué)附屬盛京醫(yī)院神經(jīng)外科工作,2005年留學(xué)日本就讀于日本浜松醫(yī)科大學(xué)神經(jīng)外科,2010年獲得醫(yī)學(xué)博士學(xué)位。同年留學(xué)美國俄亥俄州立大學(xué)醫(yī)學(xué)院神經(jīng)外科做博士后研究工作。2012年回國,在首都醫(yī)科大學(xué)三博腦科醫(yī)院神經(jīng)外科顱底腫瘤病區(qū)工作至今,任顱底病區(qū)副主任。長期從事神經(jīng)系統(tǒng)腦腫瘤的臨床和研究工作,在腦腫瘤診斷、手術(shù)治療方面有豐富的臨床經(jīng)驗。

代表性文章

1.Liu H, Sun Y, Qi X, Gordon RE, O'Brien JA, Yuan H, Zhang J, Wang Z, Zhang M, Song Y, Yu C, Gu C: EZH2 Phosphorylation Promotes Self-Renewal of Glioma Stem-Like Cells Through NF-κB Methylation. Front Oncol. 2019 Jul 16;9:641.

2.Liu H, Sun Q, Sun Y, Zhang J, Yuan H, Pang S, Qi X, Wang H, Zhang M, Zhang H, Yu C, Gu C:MELK and EZH2 Cooperate to Regulate Medulloblastoma Cancer Stem-like Cell Proliferation and Differentiation. Mol Cancer Res. 2017 Sep;15(9):1275-1286.

3. Zhang M, Wang Z, Zhang J, Zhang H, Gu C, Wang H, Yu C, Wu H:Metastases in cerebellopontine angle from the tumors of central nerve system. J Clin Neurosci. 2017 Aug;42:84-90.

4. Kim SH, Joshi K, Ezhilarasan R, Myers TR, Siu J, Gu C, Nakano-Okuno M, Taylor D, Minata M, Sulman EP, Lee J, Bhat KP, Salcini AE, Nakano I: EZH2 protects glioma stem cells from radiation-induced cell death in a MELK/FOXM1-dependent manner. Stem Cell Reports. 2015 Feb 10;4(2):226-38.

5. Minata M, Gu C, Joshi K, Nakano-Okuno M, Hong C, Nguyen CH, Kornblum HI, Molla A, Nakano I: Multi-kinase inhibitor C1 triggers mitotic catastrophe of glioma stem cells mainly through MELK kinase inhibition. PLoS One. 2014 Apr 16;9(4):e92546.

6. Gu C, Banasavadi-Siddegowda YK, Joshi K, Nakamura Y, Kurt H, Gupta S, Nakano I: Tumor-Specific Activation of the C-JUN/MELK Pathway Regulates Glioma Stem Cell Growth in a p53-Dependent Manner. Stem Cell. 2013 May;31(5):870-81.

7. Li S, Gu C, Gao Y, Amano S, Koizumi S, Tokuyama T, Namba H: Bystander effect in glioma suicide gene therapy using bone marrow stromal cells. Stem Cell Res. 2012 Nov;9(3):270-6.

8. Gu C, Yokota N, Gao Y, Amano S, Koizumi S, Tokuyama T, Namba H: Targeting therapy against promyelocytic leukemia gene using arsenic acids in experimental intracranial medulloblastoma. Neurologia medico-chirurgica, 2012;52(2):62-7.

9. Amano S, Gu C, Koizumi S, Tokuyama T, Namba H: Tumoricidal bystander effect in the suicide gene therapy using mesenchymal stem cells does not injure normal brain tissues. Cancer Lett. 2011 Jul 1;306(1):99-105.

10. Amano S, Gu C, Koizumi S, Tokuyama T, Namba H:Timing of ganciclovir administration in glioma gene therapy using HSVtk gene-transduced mesenchymal stem cells. Cancer Genomics Proteomics. 2011 Sep-Oct;8(5):245-50.

11. Koizumi S, Gu C, Amano S, Yamamoto S, Ihara H, Tokuyama T, Namba H:Migration of mouse-induced pluripotent stem cells to glioma-conditioned medium is mediated by tumor-associated specific growth factors. Oncol Lett. 2011 Mar;2(2):283-288.

12. Gu C, Yokota N, Gao Y, Yamamoto J, Tokuyama T, Namba H: Gene expression of growth signaling pathways is up-regulated in CD133-positive medulloblastoma cells. Oncol Lett. 2011 Mar;2(2):357-361.

13. Gao Y, Gu C, Li S, Tokuyama T, Yokota N, Nakayama KI, Kitagawa M, Namba H:p27 modulates tropism of mesenchymal stem cells toward brain tumors. Exp Ther Med. 2010 Jul;1(4):695-699.

14. Gu C, Li S, Tokuyama T, Yokota N, Namba H: Therapeutic effect of genetically engineered mesenchymal stem cells in rat experimental leptomeningeal glioma model. Cancer Lett. 291: 256–262, 2010.

15. Amano S, Li S, Gu C, Gao Y, Koizumi S, Yamamoto S, Terakawa S, Namba H: Tumoricidal bystander effect-mediated suicide gene therapy of glioma using genetically engineered bone marrow-drived mesenchymal stem cells. Int J Oncol. 35: 1265-1270, 2009.


團(tuán)隊其他專家

于春江

于春江

主任醫(yī)師

出診時間:周二、周四上午

張明山

張明山

主任醫(yī)師

出診時間:周二、四上午

疾病科普
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